Maoyuu Maou Yuusha - Volume 1 Chapter 10, “Take up the Sword, my Master”

A Di [legitimate-born] daughter of a noble house turns into an abandoned daughter. No father to dote on her, no mother to love her, no problem. She uses one silver needle to save a dying man. What’s so unusual about a medical injection? She roams all over the world with a scalpel in her hand. Cutting throats, cutting open abdomens, cutting open skulls to mend bones. With amazing medical skills and ethics, she gathers a flock of officials, obtains the will of heavens, gains public favor, and receives Taizi’s [Crown Prince] doting. In the midst of a powerful momentum, her cheap father comes to reunite. She coldly refuses to go home or acknowledge ancestors.

“I was abandoned by you over and over again. Now you want to use familial affection to coax me back. You don’t want to recognize this daughter. My heart is cold, I want to leave. Beat it, father!”

- Description from Novelupdates

“Brother Katakuri, I’m sorry, I don’t want to bear the name of Charlotte for a long time!”

“Ace, your flame is too weak!”

“Akainu, magma is dessert to fire dragons! Why don’t you understand this?”

The man who ate the dragon fruit, the traitor of the Charlotte family, sprinted towards the title of One Piece!

- Description from novelbuddy

In the original world, Sasuke had a tragic life experience, his entire clan was wiped out, he was deceived by Itachi, brainwashed by Obito, and played with by applause, and everything was clearly arranged!On the spur of the moment, you will get a severe beating! In the end, he cut off his hand, carried everything on his back, and left Konoha alone. The Uchiha clan fell...After Getting Transmigrated As Uchiha Sasuke, Yah Let's Definitely Try To Avoid All Of This Shit....

The challenges a female cultivator had to overcome on her life journey were countless.