The Warden of The Witches - Chapter 251:

In the original world, Sasuke had a tragic life experience, his entire clan was wiped out, he was deceived by Itachi, brainwashed by Obito, and played with by applause, and everything was clearly arranged!On the spur of the moment, you will get a severe beating! In the end, he cut off his hand, carried everything on his back, and left Konoha alone. The Uchiha clan fell...After Getting Transmigrated As Uchiha Sasuke, Yah Let's Definitely Try To Avoid All Of This Shit....

When The Cute Kunoichis Spied on Their Teacher's Secret is a light novel written by Kazuma Kamachi and illustrated by Ryuushi Tajima.

The story takes place in a world where Japan never ended their isolationist phase, and agents from foreign powers are always threatening to steal the country's advanced technology. In order to combat this threat there has been a resurgence of ninjas that use Strategic Martial Arts, techniques that combine cutting-edge modern technology with a traditional foundation of martial arts and ninjutsu. The story follows Souha Sugiyado, a 17-year old ninja instructor and former ninja prodigy who was forced to retire from active duty by the wounds he suffered in his last mission. Souha's four students are all kunoichi who have all gained the rank of Elite Ninja, the highest official rank available to ninja. However, one day two Shogunate ninja approach him with the news that his four students have gone rogue and have stolen a portable modular nuclear reactor, and thus they ask for his help in bringing his students to justice.

A Pill Emperor of his generation was set up by a traitor.

Since then, the world lost a Qingyun Zi and gained an invincible silkpants.

Once again, walking the Great Dao of Alchemy.

How can I defy the heavens . . . with the medicine in my hands!

- Description from Novelupdates