Kyoukai Senjou no Horizon - Volume 8A, Chapter 9: Crybaby at Home

After being imprisoned in the basement by her mother for ten years, she ended her cruel and tragic life in death when they forced her to hand over the key to the hidden treasure. Getting reborn in her teenage years, she woke up in the bed of that terrible and powerful man. This time, she must take revenge on her enemy, and now she must live.

I met the male lead in prison.

The genius pharmacist transmigrated into a pitiful farm girl’s body. Ignored by her own father, abused by her stepmother, and bullied by her stepbrothers. Her “twin” brother was given to distant relative and she went as the “extra” to live under someone else’s roof.

Luckily she possessed mad apothecary skills. Collecting herbs, plowing herb fields, formulating medicines and treating the ills, she refused to live an ordinary life as she slowly uncovered the truth of her real identify.

Inadvertently, she saved a dashing man who was in reality a big, bad wolf hiding under the skin of an innocent little puppy. He pulled out all his tricks: I have no other means to return your favor of saving my life. What say I repay you by marrying you?

- Description from Novelupdates

Madeline Celeste d'Aumont is the first daughter of Duke Aumont and Duchess Louise-Marie d'Aumont who has been engaged to the Second Prince of Pays Des Abrutis since she was a child. The Second Prince decided to marry a woman closer to his own age and broke off the engagement to Madeline who was left with a broken heart and a reputation as being an unwanted woman even before she was an adult. The Duke decided to help his daughter regain her confidence and reputation by sending her to the Academy de L'échec.

Ito Aoi was the son of a Kendo master who ran a dojo in downtown Tokyo. One day while crossing the street to get some Yakitori, Aoi was hit by a delivery truck and woke up as the trash first son of Duke Montfort, Guy de Montfort. Duke Montfort also sent his son to Academy de L'échec only Aoi instantly recognized that he was now living in the world of an Otome Game that his sister loved to play and talk about all the time. Aoi recognizes that Madeline is the villain from the game. Aoi also recalled his sister saying that Madeline was terrible in the game, but is she really?