The Substitute Madam Amazes the World Once More - Chapter 450 - Using Medicine to Treat The Problem

– The planet [Earth] has entered the abnormal state [Apocalypse].

Ethan was betrayed, he was broken, left crippled by those he trusted most: Zachary and Ivy, the people who ruined his life. Stripped of everything, Ethan crawled through three grueling years in the abandoned depths of despair, desperate to regain what he lost.Until one final act of defiance opened the door to something greater.When Ethan completed a hidden quest, fate granted him a miraculous reward: a second chance.He awakens years in the past, on the eve of a revolution: the launch of Ethereal, the world's first fully immersive VR game and humanity’s obsession. Armed with memories of four years in Ethereal, he’s no longer the helpless pawn who lost everything.This time, Ethan knows every secret, every hidden quest, every exploit to climb back to the top. But when he steps into the game, the system unveils a shocking twist: a divine bloodline, legendary abilities, and a class no one believed could dominate.Ethan vows to rise once more, but this time, he knows where the paths of glory begin, where betrayal lurks, and where to find legendary treasures that will crown him king in this brutal new world.The stakes are higher than ever. Factions are forming, alliances are shattering, and the clock ticks toward an event that will rewrite reality itself.The weak will perish, and the strong will thrive.They betrayed him once.They won’t live to do it again.

The young man was so ridiculed for his wasted blood aptitude. Once he awakened the supreme bloodline, the dragon flew into the sky!

From then on, the geniuses and martial arts giants all bowed their heads, and the nine heavens and ten earth trembled!

Condensing the supreme Taoist body to achieve supreme power!

One finger penetrates the plane, one sword slashes the galaxy, one thought swallows the starry sky, and holds the avenue for eternity!

- Description from MTL

The world was never the same after that day.Humanity learned that they weren't alone in the universe, but that wasn't something they had the time to worry about.Their realization was accompanied by catastrophe.Creatures beyond their wildest imaginations poured down from the sky and appeared from the earth. They slaughtered humans as if it was their singular purpose, driving them to the brink of extinction.The people of the world did everything in their power, developing unique traits and technologies to create a united front their enemies couldn't penetrate.They secured victories and repopulated, feeling as if they stood a chance against the foreign invaders.They fought and they fought, doing everything they possibly could to ensure their survival.Until the Great Calamities appeared.In front of them, humanity was nothing regardless of its efforts.One by one, the worlds were turned into piles of rubble in between the cracks of their teeth. Civilization was torn apart, and the evolved humans living within could do nothing to stop its collapse.Humanity itself was left extinct, and in the end, only a single man was left alive amidst the chaos.Why?For what reason were they punished so?Nobody knew why the attacks began in the first place.He looked into the distance at the memories of the past and firmed his resolve.“It can only be me.”He knew of a miracle that could return him to the place of those memories.He knew of a way to make the wheels of time spin in reverse.And using it, he alone would save humanity from its doomed fate.That was his sacred duty as its final survivor.